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Ultra-high Performance Liquid Chromatography- Triple Quadrupole Mass Spectrometry

Author: Source:  Popularity:  Addtime:2014-09-25 11:12:00



Name of Instrument: Name: Ultra-high Performance Liquid Chromatography- Triple Quadrupole Mass Spectrometry

Type and Specification: Agilent 1290-6495

Manufacturer: Agilent

Purchase Time: 2014

Main Uses: The detection and analysis to complicated samples, including food, agricultural products, and environment and so on, and to residues of organic pollutants, such as polar pesticides, antibiotics and veterinary drug; the fast and efficient separation and quantitative analysis are also available.

Technical Indexes:

1. Double- plunger reciprocating pump in series, variable stroke of servo control and smooth movement control; automatic clearing apparatus of plunger, including vacuum on- line deaerator;

2. Operating Pressure: 0~1200 bar;

3. Range of Velocity: 0.001~3.0mL/min, 0.001mL/min step;

4. Velocity precision<0.07%RSD;

5. Gradient composition precision<0.15% RSD, gradient composition accuracy: ±0.4%;

6. The range of injection is 0.1~ 20μL, injection precision<0.25% RSD;

7. Range of temperature control is 10℃- 95℃ in the room, and the semiconductor temp- enclosure column heater can be heating and cooling;

8. Rate of temperature control: 5 min from the room temperature to 40℃, and 10 min from 40℃ down to 20℃;

9. Stabilization of column temperature: ±0.05℃;

10. Two 30cm chromatographic columns can be contained at a time;

11. Main engine of triple- quadrupole tandem mass spectrometer;

12. Mass range ( m/z): 10~ 2200 amu;

13. Positive iron of ESI: in 4.1mm×30mm, 3.5μm SB-C18, 1pg Reserpine is above column at 400μL/min, with iron to m/z 609>195, S/N>120,000: 1, and the detection limit of IDL instrument is 0.8 fg;

14. Negative iron of ESI: 1 pg chloramphenicol, m/z312>152, the signal- to- noise ratio≥120, 000:1; the detection limit of IDL instrument is 0.8 fg;

15. Mass accuracy<0.01%;

16. Mass stabilization<0.1amu (24hr);

17. Maximum resident time of MRM: 1 ms;

18. 500 MRM can be collected per second;

19. The tuning and correcting system of mass spectrometry: the tuning and correcting system can be tuned and corrected automatically;

20. The high purity nitrogen is applied to be the atomization gas and collision gas, and the extra argon is not needed;

21. Detection system: the double dynode and electron multiplier

22. High resolution mass number detector, and the series system is made up by the quadrupole/ time of flight;

23. Automatically switch between MS and MS/MS according to data;

24. The standard allocation of atmospheric pressure ion source is ESCI compound ion source, and at the same time, it is to implement the detection of electron spray ionization source( ESI) and atmospheric pressure chemical ionization source( APCI), with the switch rate between ESI and APCI≤22ms;

25. The built- in automatic injection pump has injection bottles with more than two ways by itself to implement the automatic resonance and correction of mass spectrometry and the injection analysis directly;

26. The ion source has the double temperature control region, and the ion source can be heated to 600℃ or more;

27. The mass precision, the external standard method MS and MS/ MS mode are down to <1ppm;

28. Sensitivity: under the 1 pg reserpine on- column injection MS mode, S/N≥1200:1.


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